High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons
Wong, Yue Him1; Sun, Jin2; He, Li Sheng3; Chen, Lian Guo1; Qiu, Jian-Wen2; Qian, Pei-Yuan1
2015-11-23
Source PublicationSCIENTIFIC REPORTS
Volume5
AbstractBathymodiolid mussels dominate hydrothermal vents, cold methane/sulfide-hydrocarbon seeps, and other sites of organic enrichment. Here, we aimed to explore the innate immune system and detoxification mechanism of the deep sea mussel Bathymodiolus platifrons collected from a methane seep in the South China Sea. We sequenced the transcriptome of the mussels' gill, foot and mantle tissues and generated a transcriptomic database containing 96,683 transcript sequences. Based on GO and KEGG annotations, we reported transcripts that were related to the innate immune system, heavy metal detoxification and sulfide metabolic genes. Our in-depth analysis on the isoforms of peptidoglycan recognition protein (PGRP) that have different cellular location and potentially differential selectivity towards peptidoglycan (PGN) from gram-positive and gram-negative bacteria were differentially expressed in different tissues. We also reported a potentially novel form of metallothionein and the production of phytochelatin in B. platifrons, which has not been reported in any of its coastal relative Mytilus mussel species. Overall, the present study provided new insights into heavy metal and sulfide metabolism in B. platifrons and can be served as the basis for future molecular studies on host-symbiont interactions in cold seep mussels.
SubtypeArticle
WOS HeadingsScience & Technology
DOI10.1038/srep16597
Indexed BySCI
Language英语
WOS KeywordPEPTIDOGLYCAN RECOGNITION PROTEIN ; HEAVY-METAL DETOXIFICATION ; OUTER-MEMBRANE PROTEIN ; DEEP-SEA MUSSELS ; HYDROTHERMAL VENTS ; TAURINE TRANSPORTER ; METHANE SEEP ; RNA-SEQ ; THIOTROPHIC ENDOSYMBIONTS ; PHYTOCHELATIN SYNTHASE
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000365085100001
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Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.idsse.ac.cn/handle/183446/893
Collection深海科学研究部_深海生物学研究室_深海无脊椎动物蛋白质组学及分子生物学研究组
Affiliation1.Hong Kong Univ Sci & Technol, Sch Sci, Div Life Sci, Hong Kong, Hong Kong, Peoples R China
2.Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China
3.Chinese Acad Sci, Sanya Inst Deep Sea Sci & Engn, Hainan, Peoples R China
Recommended Citation
GB/T 7714
Wong, Yue Him,Sun, Jin,He, Li Sheng,et al. High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons[J]. SCIENTIFIC REPORTS,2015,5.
APA Wong, Yue Him,Sun, Jin,He, Li Sheng,Chen, Lian Guo,Qiu, Jian-Wen,&Qian, Pei-Yuan.(2015).High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons.SCIENTIFIC REPORTS,5.
MLA Wong, Yue Him,et al."High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons".SCIENTIFIC REPORTS 5(2015).
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