Genomic Characterization of a Novel Gut Symbiont From the Hadal Snailfish
Lian, Chun-Ang1,2; Yan, Guo-Yong1,2; Huang, Jiao-Mei1,2; Danchin, Antoine3; Wang, Yong1; He, Li-Sheng1
2020-01-10
Source PublicationFRONTIERS IN MICROBIOLOGY
ISSN1664-302X
Volume10Issue:1Pages:10
Abstract

Hadal trenches are characterized by not only high hydrostatic pressure but also scarcity of nutrients and high diversity of viruses. Snailfishes, as the dominant vertebrates, play an important role in hadal ecology. Although studies have suggested possible reasons for the tolerance of hadal snailfish to high hydrostatic pressure, little is known about the strategies employed by hadal snailfish to cope with low-nutrient and virus-rich conditions. In this study, the gut microbiota of hadal snailfish was investigated. A novel bacterium named "Candidatus Mycoplasma liparidae" was dominant in the guts of three snailfish individuals from both the Mariana and Yap trenches. A draft genome of "Ca. Mycoplasma liparidae" was successfully assembled with 97.8% completeness by hybrid sequencing. A set of genes encoding riboflavin biosynthesis proteins and a clustered regularly interspaced short palindromic repeats (CRISPR) system was present in the genome of "Ca. Mycoplasma liparidae," which was unusual for Mycoplasma. The functional repertoire of the "Ca. Mycoplasma liparidae" genome is likely set to help the host in riboflavin supplementation and to provide protection against viruses via a super CRISPR system. Remarkably, genes encoding common virulence factors usually exist in Tenericutes pathogens but were lacking in the genome of "Ca. Mycoplasma liparidae." All of these characteristics supported an essential role of "Ca. Mycoplasma liparidae" in snailfish living in the hadal zone. Our findings provide further insights into symbiotic associations in the hadal biosphere.

Keywordhadal symbiosis Tenericutes CRISPR snailfish metagenome
DOI10.3389/fmicb.2019.02978
Indexed BySCI
Funding OrganizationKey R&D Program of China ; Strategic Priority Research Program B of the Chinese Academy of Sciences (CAS)
Language英语
Funding ProjectKey R&D Program of China[2018YFC0309804] ; Key R&D Program of China[2016YFC0302504] ; Key R&D Program of China[2018YFC0310005] ; Strategic Priority Research Program B of the Chinese Academy of Sciences (CAS)[XDB06010103] ; Strategic Priority Research Program B of the Chinese Academy of Sciences (CAS)[XDB06010201]
WOS KeywordCRISPR-CAS SYSTEMS ; DEEPEST OCEAN ; MICROBIOTA ; VIRULENCE ; BACTERIA ; SEQUENCE ; GENES ; HOST ; CLASSIFICATION ; EVOLUTION
WOS Research AreaMicrobiology
WOS SubjectMicrobiology
WOS IDWOS:000509253500001
PublisherFRONTIERS MEDIA SA
Citation statistics
Document Type期刊论文
Version出版稿
Identifierhttp://ir.idsse.ac.cn/handle/183446/7390
Collection深海科学研究部_深海生物学研究室_深海生物蛋白质组学及分子生物学研究组
研究生部
深海科学研究部_深海生物学研究室_深海微生物基因组学研究组
Corresponding AuthorWang, Yong; He, Li-Sheng
Affiliation1.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Peoples R China
2.Univ Chinese Acad Sci, Coll Earth Sci, Beijing, Peoples R China
3.Univ Paris 05, CNRS UMR 8104, INSERM U1016, Dept Infect Immun & Inflammat,Inst Cochin, Paris, France
First Author AffilicationInstitute of Deep-sea Science and Engineering,CAS
Corresponding Author AffilicationInstitute of Deep-sea Science and Engineering,CAS
Recommended Citation
GB/T 7714
Lian, Chun-Ang,Yan, Guo-Yong,Huang, Jiao-Mei,et al. Genomic Characterization of a Novel Gut Symbiont From the Hadal Snailfish[J]. FRONTIERS IN MICROBIOLOGY,2020,10(1):10.
APA Lian, Chun-Ang,Yan, Guo-Yong,Huang, Jiao-Mei,Danchin, Antoine,Wang, Yong,&He, Li-Sheng.(2020).Genomic Characterization of a Novel Gut Symbiont From the Hadal Snailfish.FRONTIERS IN MICROBIOLOGY,10(1),10.
MLA Lian, Chun-Ang,et al."Genomic Characterization of a Novel Gut Symbiont From the Hadal Snailfish".FRONTIERS IN MICROBIOLOGY 10.1(2020):10.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Lian, Chun-Ang]'s Articles
[Yan, Guo-Yong]'s Articles
[Huang, Jiao-Mei]'s Articles
Baidu academic
Similar articles in Baidu academic
[Lian, Chun-Ang]'s Articles
[Yan, Guo-Yong]'s Articles
[Huang, Jiao-Mei]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Lian, Chun-Ang]'s Articles
[Yan, Guo-Yong]'s Articles
[Huang, Jiao-Mei]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.