Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes
Yang, Liandong1; Jiang, Haifeng1,2; Chen, Juan1,2; Lei, Yi1,2; Sun, Ning1,2; Lv, Wenqi1,2; Near, Thomas J.3,4; He, Shunping1,5,6
2019-12-23
Source PublicationFRONTIERS IN GENETICS
Volume10Pages:15
Abstract

The ostariophysian fishes are the most species-rich clade in freshwaters. This diversification has been suggested to be associated with the fright reaction presented in most ostariophysians. However, the genetic forces that underlie fright reaction remains poorly understood. In the present study, through integrating behavioral, physiological, transcriptomic, and evolutionary genomic analyses, we found that the fright reaction has a broad impact on zebrafish at multiple levels, including changes in swimming behaviors, cortisol levels, and gene expression patterns. In total, 1,555 and 1,599 differentially expressed genes were identified in olfactory mucosae and brain of zebrafish, respectively, with a greater number upregulated after the fright reaction. Functional annotation showed that response to stress and signal transduction were strongly represented, which is directly associated with the fright reaction. These differentially expressed genes were shown to be evolved accelerated under the influence of positive selection, indicating that protein-coding evolution has played a major role in fright reaction. We found the basal vomeronasal type 2 receptors (v2r) gene, v2rl1, displayed significantly decrease expression after fright reaction, which suggests that v2rs may be important to detect the alarm substance and induce the fright reaction. Collectively, based on our transcriptome and evolutionary genomics analyses, we suggest that transcriptional plasticity of gene may play an important role in fright reaction in ostariophysian fishes.

Keywordostariophysans fright reaction RNA-seq accelerated evolution positive selection
DOI10.3389/fgene.2019.01283
Indexed BySCI
Funding OrganizationNational Natural Science Foundation of China ; Institute of Hydrobiology, Chinese Academy of Sciences ; Wuhan Branch, Supercomputing Center, Chinese Academy of Sciences, China
Language英语
Funding ProjectNational Natural Science Foundation of China[91731301] ; National Natural Science Foundation of China[31972866] ; National Natural Science Foundation of China[31601858] ; Institute of Hydrobiology, Chinese Academy of Sciences[Y55Z09] ; Institute of Hydrobiology, Chinese Academy of Sciences[Y85E03] ; Wuhan Branch, Supercomputing Center, Chinese Academy of Sciences, China
WOS KeywordOLFACTORY RECEPTOR ; ADAPTIVE EVOLUTION ; BIASED GENES ; EXPRESSION PATTERN ; DIFFERENTIAL GENE ; CODON USAGE ; ZEBRAFISH ; STRESS ; DROSOPHILA ; RESPONSES
WOS Research AreaGenetics & Heredity
WOS SubjectGenetics & Heredity
WOS IDWOS:000506010300001
PublisherFRONTIERS MEDIA SA
Citation statistics
Document Type期刊论文
Version出版稿
Identifierhttp://ir.idsse.ac.cn/handle/183446/7372
Collection深海科学研究部_深海生物学研究室_深海鱼类物种与基因组多样性的研究
Corresponding AuthorNear, Thomas J.; He, Shunping
Affiliation1.Chinese Acad Sci, Key Lab Aquat BiodiVers & Conservat, Inst Hydrobiol, Wuhan, Hubei, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Yale Univ, Dept Ecol & Evolutionary Biol, New Haven, CT 06520 USA
4.Yale Univ, Peabody Museum Nat Hist, New Haven, CT 06520 USA
5.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Peoples R China
6.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming, Yunnan, Peoples R China
Corresponding Author AffilicationInstitute of Deep-sea Science and Engineering,CAS
Recommended Citation
GB/T 7714
Yang, Liandong,Jiang, Haifeng,Chen, Juan,et al. Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes[J]. FRONTIERS IN GENETICS,2019,10:15.
APA Yang, Liandong.,Jiang, Haifeng.,Chen, Juan.,Lei, Yi.,Sun, Ning.,...&He, Shunping.(2019).Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes.FRONTIERS IN GENETICS,10,15.
MLA Yang, Liandong,et al."Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes".FRONTIERS IN GENETICS 10(2019):15.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yang, Liandong]'s Articles
[Jiang, Haifeng]'s Articles
[Chen, Juan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yang, Liandong]'s Articles
[Jiang, Haifeng]'s Articles
[Chen, Juan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yang, Liandong]'s Articles
[Jiang, Haifeng]'s Articles
[Chen, Juan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.