Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes
Sun, Jin1,2; Zhang, Yu3; Xu, Ting2; Zhang, Yang4; Mu, Huawei2; Zhang, Yanjie2; Lan, Yi1; Fields, Christopher J.5; Hui, Jerome Ho Lam6; Zhang, Weipeng1; Li, Runsheng2; Nong, Wenyan6; Cheung, Fiona Ka Man6; Qiu, Jian-Wen2; Qian, Pei-Yuan1,7; Qiu, Jian-Wen(Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China); Qian, Pei-Yuan(Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China)
2017-05-01
Source PublicationNATURE ECOLOGY & EVOLUTION
Volume1Issue:5
Contribution Rank第1完成单位 ; 第2完成单位 ; 第3完成单位 ; 第4完成单位 ; 第5完成单位 ; 第6完成单位 ; 第7完成单位
AbstractHydrothermal vents and methane seeps are extreme deep-sea ecosystems that support dense populations of specialized macrobenthos such as mussels. But the lack of genome information hinders the understanding of the adaptation of these animals to such inhospitable environments. Here we report the genomes of a deep-sea vent/seep mussel (Bathymodiolus platifrons) and a shallow-water mussel (Modiolus philippinarum). Phylogenetic analysis shows that these mussel species diverged approximately 110.4 million years ago. Many gene families, especially those for stabilizing protein structures and removing toxic substances from cells, are highly expanded in ft, platifrons, indicating adaptation to extreme environmental conditions. The innate immune system of B. platifrons is considerably more complex than that of other lophotrochozoan species, including M. philippinarum, with substantial expansion and high expression levels of gene families that are related to immune recognition, endocytosis and caspase-mediated apoptosis in the gill, revealing presumed genetic adaptation of the deep-sea mussel to the presence of its chemoautotrophic endosymbionts. A follow-up metaproteomic analysis of the gill of B. platifrons shows methanotrophy, assimilatory sulfate reduction and ammonia metabolic pathways in the symbionts, providing energy and nutrients, which allow the host to thrive. Our study of the genomic composition allowing symbiosis in extremophile molluscs gives wider insights into the mechanisms of symbiosis in other organisms such as deep-sea tubeworms and giant clams.
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1038/s41559-017-0121
URL查看原文
Indexed BySCI
Language英语
WOS KeywordBATHYMODIOLUS-AZORICUS ; MAXIMUM-LIKELIHOOD ; ENDOSYMBIONTS ; ENDOCYTOSIS ; APOPTOSIS ; SYMBIOSIS ; ANIMALS ; MODEL ; FLUID
WOS SubjectEcology ; Evolutionary Biology
WOS IDWOS:000417173100011
Citation statistics
Cited Times:44[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.idsse.ac.cn/handle/183446/5917
Collection深海科学研究部_深海生物学研究室_海洋哺乳动物与海洋生物声学研究组
Corresponding AuthorQiu, Jian-Wen; Qian, Pei-Yuan; Qiu, Jian-Wen(Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China); Qian, Pei-Yuan(Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China)
Affiliation1.Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China
2.Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China
3.Shenzhen Univ, Coll Life Sci, Shenzhen Key Lab Marine Bioresource & Ecoenvironm, Shenzhen, Peoples R China
4.Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China
5.Univ Illinois, Roy J Carver Biotechnol, High Performance Comp Biol, Urbana, IL 61801 USA
6.Chinese Univ Hong Kong, Ctr Soybean Res, Partner State Key Lab Agrobiotechnol, Simon FS Li Marine Sci Lab,Sch Life Sci, Hong Kong, Hong Kong, Peoples R China
7.Sanya Inst Deep Sea Sci & Engn, HKUST CAS Joint Lab, Sanya 572000, Peoples R China
Recommended Citation
GB/T 7714
Sun, Jin,Zhang, Yu,Xu, Ting,et al. Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes[J]. NATURE ECOLOGY & EVOLUTION,2017,1(5).
APA Sun, Jin.,Zhang, Yu.,Xu, Ting.,Zhang, Yang.,Mu, Huawei.,...&Qian, Pei-Yuan.(2017).Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes.NATURE ECOLOGY & EVOLUTION,1(5).
MLA Sun, Jin,et al."Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes".NATURE ECOLOGY & EVOLUTION 1.5(2017).
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