Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004
Han, Zhuang1,2; Li, Yong-Xin2; Liu, Ling-Li2; Lu, Liang2; Guo, Xian-Rong3; Zhang, Xi-Xiang4; Zhang, Xiao-Yong5; Qi, Shu-Hua5; Xu, Ying2,6; Qian, Pei-Yuan2; Qian PY; Xu, Ying(Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China); Qian, Pei-Yuan(Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China)
2017-05-01
Source PublicationMARINE DRUGS
Volume15Issue:5Pages:128
Contribution Rank第1完成单位 ; 第2完成单位 ; 第3完成单位 ; 第4完成单位 ; 第5完成单位 ; 第6完成单位
AbstractEleven new depsides-thielavins W-Z (1-4) and thielavins Z(1)-Z(7) (5-11)-and also four known thielavins-A, H, J, and K (12-15)-were isolated from the ethyl acetate extract of a marine-derived fungal strain Thielavia sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle Balanus (=Amphibalanus) amphitrite. The results showed that compounds 1-3 and 6-13 were active, with EC50 values ranging from 2.95 +/- 0.59 to 69.19 +/- 9.51 mu M, respectively. The inhibitive effect of compounds 1-3 and 7 was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids.
SubtypeArticle
KeywordMarine-derived Fungus Thielavia Sp. Antifouling Balanus (=amphiBalanus) Amphitrite Thielavins
Subject Area海洋生物学
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.3390/md15050128
URL查看原文 ; 查看原文
Indexed BySCI
Language英语
WOS KeywordBIOLOGICAL-ACTIVITIES ; BALANUS-AMPHITRITE ; INHIBITORS ; SETTLEMENT ; COMPOUND
WOS SubjectChemistry, Medicinal
WOS IDWOS:000404235100004
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.idsse.ac.cn/handle/183446/2378
Collection深海科学研究部_深海生物学研究室_深海微生物活性物质研究组
Corresponding AuthorXu, Ying; Qian, Pei-Yuan; Qian PY; Xu, Ying(Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China); Qian, Pei-Yuan(Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China)
Affiliation1.Chinese Acad Sci, Inst Deep Sea Sci & Engn, 28 Luhuitou Rd, Sanya 572000, Peoples R China
2.Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China
3.King Abdullah Univ Sci & Technol, Imaging & Characterizat Core Lab, Thuwal 239556900, Saudi Arabia
4.King Abdullah Univ Sci & Technol, Phys Sci & Engn, Thuwal 239556900, Saudi Arabia
5.Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China
6.Shenzhen Univ, Coll Life Sci, 3688 Nanhai Ave, Shenzhen 518060, Peoples R China
Recommended Citation
GB/T 7714
Han, Zhuang,Li, Yong-Xin,Liu, Ling-Li,et al. Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004[J]. MARINE DRUGS,2017,15(5):128.
APA Han, Zhuang.,Li, Yong-Xin.,Liu, Ling-Li.,Lu, Liang.,Guo, Xian-Rong.,...&Qian, Pei-Yuan.(2017).Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004.MARINE DRUGS,15(5),128.
MLA Han, Zhuang,et al."Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004".MARINE DRUGS 15.5(2017):128.
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