Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting
Zhang, Gen1,2; Wong, Yue-Him2; Zhang, Yu3; He, Li-Sheng4; Xu, Ying3; Qian, Pei-Yuan1,2
2015-11-01
Source PublicationPROTEOMICS
Volume15Issue:22Pages:3854-3864
AbstractNitric oxide (NO) is a universal signaling molecule and plays a negative role in the metamorphosis of many biphasic organisms. Recently, the NO/cGMP (cyclic guanosine monophosphate) signaling pathway was reported to repress larval settlement in the barnacle Amphibalanus amphitrite. To understand the underlying molecular mechanism, we analyzed changes in the proteome of A. amphitrite cyprids in response to different concentrations of the NO donor sodium nitroprusside (SNP; 62.5, 250, and 1000 mu M) using a label-free proteomics method. Compared with the control, the expression of 106 proteins differed in all three treatments. These differentially expressed proteins were assigned to 13 pathways based on KEGG pathway enrichment analysis. SNP treatment stimulated the expression of heat shock proteins and arginine kinase, which are functionally related to NO synthases, increased the expression levels of glutathione transferases for detoxification, and activated the iron-mediated fatty acid degradation pathway and the citrate cycle through ferritin. Moreover, NO repressed the level of myosins and cuticular proteins, which indicated that NO might inhibit larval settlement in A. amphitrite by modulating the process of muscle locomotion and molting.
SubtypeArticle
KeywordAnimal Proteomics Barnacle Label-free Quantification Ms Nitric Oxide
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1002/pmic.201500112
URL查看原文
Indexed BySCI
Language英语
WOS KeywordSNAIL ILYANASSA-OBSOLETA ; PROGRAMMED CELL-DEATH ; SMOOTH-MUSCLE ; CREPIDULA-FORNICATA ; OXIDATIVE STRESS ; NERVOUS-SYSTEM ; L-ARGININE ; METAMORPHOSIS ; SYNTHASE ; IRON
WOS SubjectBiochemical Research Methods ; Biochemistry & Molecular Biology
WOS IDWOS:000367727800010
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.idsse.ac.cn/handle/183446/1343
Collection深海科学研究部_深海生物学研究室_深海无脊椎动物蛋白质组学及分子生物学研究组
Affiliation1.Hong Kong Univ Sci & Technol, Environm Sci Programs, Sch Sci, Kowloon, Hong Kong, Peoples R China
2.Hong Kong Univ Sci & Technol, Div Life Sci, KAUST Global Collaborat Res Program, Kowloon, Hong Kong, Peoples R China
3.Shenzhen Univ, Coll Life Sci, Shenzhen Key Lab Marine Bioresource & Ecoenvironm, Shenzhen, Peoples R China
4.Chinese Acad Sci, Sanya Inst Deep Sea Sci & Engn, Sanya City, Hainan Province, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Gen,Wong, Yue-Him,Zhang, Yu,et al. Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting[J]. PROTEOMICS,2015,15(22):3854-3864.
APA Zhang, Gen,Wong, Yue-Him,Zhang, Yu,He, Li-Sheng,Xu, Ying,&Qian, Pei-Yuan.(2015).Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting.PROTEOMICS,15(22),3854-3864.
MLA Zhang, Gen,et al."Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting".PROTEOMICS 15.22(2015):3854-3864.
Files in This Item: Download All
File Name/Size DocType Version Access License
2015-7-Nitric oxide (910KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhang, Gen]'s Articles
[Wong, Yue-Him]'s Articles
[Zhang, Yu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhang, Gen]'s Articles
[Wong, Yue-Him]'s Articles
[Zhang, Yu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhang, Gen]'s Articles
[Wong, Yue-Him]'s Articles
[Zhang, Yu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 2015-7-Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.